Embolic Strokes after Self-Hanging
Embolic Strokes after Self-Hanging
This is somewhat unusual case. The patient in his 50’s presented after a suicide attempt via self-hanging. The patient had a cardiac arrest immediately after he was found. The heart rhythm was reported to be asystole by the paramedics. He was successfully resuscitated after ten minutes of CPR.
Therapeutic hypothermia protocol was initiated and the patient subsequently was taken off the ventilator. After his sedation was discontinued, he was noted to have several neurological deficits including right arm weakness.
MRI brain confirmed the presence of several bilateral embolic strokes. There was no dissection of his carotid arteries on the MRA of the brain/neck.
The etiology of these embolic strokes is unclear at this point. I suspect that several atherosclerotic plaques were dislodged as a result of the neck compression due to self-hanging. The patient recovered with some neurological deficits and was discharged to Rehab.
Tracheal Stent
The patient with locally advanced squamous cell carcinoma of the esophagus developed tracheoesophageal fistula. The patient was a poor candidate for surgical treatment. Combined chemo and radiation therapy was attempted.
Two overlapping tracheal stents were placed for tracheoesophageal fistula (see image above).
Temporal Lobectomy for Seizure Disorder
56 year old female with a history of progressive Multiple Sclerosis developed a medically intractable seizure disorder. The patient was tried on a combination of multiple antiepileptic medications without improvement.
The patient underwent seizure “mapping” with a seizure focus being localized to her right temporal lobe. She underwent a successful surgical temporal lobectomy with improvement in the seizure pattern.
On the CT image above note a practically absent temporal lobe on the right.
The patient did experience some cognitive and memory decline as a result of this surgery.
Unusual Presentation of Subdural Hematoma
A 90 year old female presented to her local hospital after her family found her to be having difficulty speaking. She was a pretty healthy and active 90 year old. She did have a history of atrial fibrillation and pulmonary emboli and therefore she was on Warfarin.
Upon presentation to her local ER, the physician did find her to have expressive and probably receptive aphasia. Her INR was therapeutic at 2.0. She underwent a noncontrast CT scan of the brain (image above) showing the left subdural hematoma with subfalcine herniation. A Neurosurgical consultation was obtained and the patient was transferred to my NeuroIntensive Care Unit.
The consulting Neurosurgeon was not impressed by the presentation of aphasia and elected to observe her in the ICU. Overnight her aphasia started to improve and then worsen again. A repeat CT showed the same subdural. The patient went to the OR later that day for evacuation.
I was always taught that a subdural hematoma with neurological findings was a surgical emergency. I was confused as to why the Neurosurgeon did not think so. I think I know the answer. Aphasia is not a usual presentation of a subdural hematoma (SDH).
To briefly review, head trauma is the leading cause of SDH usually related to car accidents, falls and assaults. Diffuse cerebral atrophy and the use of anticoagulation round out the list. A seemingly spontaneous unprovoked SDH occurs only 2.6% of the time.
The clinical finding associated with acute SDH is coma in 50% of cases. Posterior fossa SDH presents with symptoms of increased intracranial pressure like headache, vomiting. ataxia. Chronic SDH hematoma usually presents with headache, lightheadedness, apathy and somnolence.
Interestingly in my review, I did not find an aphasia as presenting symptom for SDH. I did find 2 studies- one from the Annals of Neurology which had 4 patients with aphasia and SDH and one form the Journal of American Medical Directors Assocation which had 1 patient with aphasia as a presenting symptom. Having seen this literature I understood a little bit more why the Neurosurgeon was not initially impressed with the case. Next time I will be an even more educated advocate for my patient in terms of needing to go to the OR with SDH presents with aphasia.
A RealICU Clinical Challenge – Lesions in the Brain and Lungs.
59 year old male with a history of non-ischemic cardiomyopathy, status post AICD/pacemaker insertion, presented with generalized weakness and confusion. He was diagnosed with diffuse B-cell lymphoma and underwent bone marrow transplant about a year ago.
The patient was on Warfarin (Coumadin) for his cardiomyopathy. Three days prior to admission he fell in the bathroom and hit his head. On presentation to the Hospital his INR was elevated at 4.1 with the platelet count of 17,000 (normal>150,000). He had low grade fever and normal white count. Cultures were obtained.
CT head showed a lesion in the right frontal area. MRI is not possible due to the AICD. CT Chest revealed multiple pulmonary nodules (see the image above).
The patient is a farmer and was working with hay several days prior to admission. He was started on an antifungal agent (voriconazole) for possible fungal infection. Bronchoscopy and biopsy was scheduled.
What is the likely etiology of the lesion in the brain and in his lungs?
Intubation for Combativeness Is a Medical Problem
How many times have I been asked by the trauma surgeons to see a trauma patient for respiratory failure? The reason for intubation and ventilatory support – being combative and non-cooperative.
Intubating, sedating and sometimes even paralyzing a combative patient is an established practice. Combative patients are dangerous to themselves and to the medical staff. Clinical and radiological evaluation of these patients is difficult as well. Asking “What is hurting, Sir” if the patient is kicking, screaming, biting and spitting is unlikely to yield any clinically useful information. Getting an extremely agitated patient to a CT scanner could be a great challenge.
Most of those patients end up on a ventilator only temporarily. Once the effects of alcohol and drugs that had been taken wears off the patient is taken off the ventilator. In some cases serious injuries could be found that would require extended ventilatory support.
Intubation or insertion of a breathing tube could be associated with complications. Especially when performed urgently and in the field conditions, the patient can experience hypoxemia (low oxygen level), aspiration of gastric contents into the lungs and damage to the vocal cords. Sedatives and paralytics used for intubation can interfere with the neurological exam and clinical evaluation.
A study published in the June issue of the Journal of Trauma compares outcomes between two groups of patients. The patients in the first group were intubated for combativeness. The patients in the second group were similar patients in all aspects, yet they were not intubated.
The results of this study are not surprising. When intubated for combativeness, patients had longer hospital stays, more frequent respiratory complications and poorer discharge status.
The authors proposed that combativeness in some patients could be a manifestation of a traumatic brain injury even if a CT head was negative for acute pathology. It is true – some patients with head injury could have an unremarkable CT scans.
The authors also suggested using sedating medications like Haldol and Benzodiazepines to control agitation and avoid intubation.
In my personal experience, many combative patients “fail” a less radical sedation prior to being put on a ventilator.
Interestingly, even though this is a very recently printed article, it was submitted for publication back in July of 2006. Using a newer drug Precedex might be helpful to control extreme agitation. Next time I get asked to see a patient with “respiratory failure from being obnoxious” I will suggest it to the surgeon.
Renal Artery Stenting for Bleeding
Renal artery angioplasty and stenting are becoming more common nowadays. Even though still controversial, stenting is being utilized to treat renal artery stenosis. It has been used more frequently if renovascular hypertension is suspected. An unusual implementation of stenting is described below.
The patient presented after a high-speed motor vehicle accident. The patient was hypotensive and complaining of left-sided abdominal pain. CT abdomen/pelvis with IV contrast showed active extravasation from the renal artery.
The patient was promptly taken to the angiography suite where the extravasation (bleeding) from the renal artery was confirmed. See the upper image above with the arrow pointing to the extravasating contrast.
One of the treatment options was to embolize the bleeding vessel. This would likely cause left kidney failure, but would also stop the bleeding and help to avoid emergent surgery (nephrectomy or kidney removal)
The interventional radiologist was able to deploy a stent (expandable metal coil) into the renal artery, ceasing further bleeding (see the bottom image above).
The patient remains hemodynamically stable with no hematuria (blood in urine) and normal renal function.
Chest Injury – Pain Control is Priority
When I was called to see the patient after a motorcycle accident I expected the worst. The patient sustained a thoracic spine injury with cord transsection at T5 level as well as significant chest wall injury on the right side.
Multiple ribs were broken; some with a significant displacement (see the upper image above). Managing patients with a significant chest wall trauma could be a nightmare. Pain control is only one of the challenges.
Mechanics of the respiratory mechanism is impaired. Patients often are unable to take a deep breath and fully expand their lungs. Clearance of the secretions is a concern as well. Many patients with severe chest wall injury succumb to pneumonia and respiratory failure.
To facilitate pulmonary clearance, improve pain control and pulmonary mechanics chest wall stabilization has become a practical option. The technique of realigning and stabilizing ribs with metal plates is yet to be widely adopted. I have witnessed on multiple occasions that the patients with a stabilized chest do better and recover faster then the patients treated conservatively.
I was surprised to see that the patient was, actually, doing Ok from the respiratory standpoint. He was describing that he could feel his whole right side of the chest shifting when he was being moved. Besides that, pain was not a major issue and his respiratory status, otherwise, was stable.
The explanation for this surprising “wellness” was not in any way satisfying. He also sustained a severe spine injury with cord transsection at T5 level. His sensory level was just below his nipples. The patient simply could not feel the pain from the chest injury.
In no way I can call it even a mixed blessing. Most of us would likely take severe pain over being paralyzed.
It did make me think, nevertheless, about the importance of pain control in these trauma patients. Huge doses of narcotics are often unable to control the discomfort. Epidural analgesia is frequently employed to alleviate the pain. Some centers even utilize pain control techniques like intercostal blocks to achieve analgesia.
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Brain Death to Organ Donation – Does it Matter How Soon?
Currently more than 100,000 patients are on the organ transplant list in the US alone. Many patients die each year without receiving a life saving organ. Increasing organ donation rates will improve this situation and will save many lives.
One of the biggest sources for organ donation are the patients with severe traumatic brain injuries who progress to brain death. Even after the patient is pronounced brain dead there is often a delay in time until organ procurement takes palce. Obtaining consent for organ donation from the family is one of the biggest obstacles towards a successful donation.
Does it matter how soon the organs are taken after the patient is declared brain dead? Does it decrease the viability of organs and reduce the number of organs harvested if the waiting time is prolonged?
Currently there is no maximum established waiting time from the onset of brain death to when a successful donation is possible. A study published in the June issue of the Trauma Journal attempts to answer those questions. The study was conducted in Southern California.
The authors of this study found no decrease in the proportion of organ procurement with a longer waiting time. Indeed, according to this publication, a successful organ donation is possible even more than 60 hours after brain death.
Furthermore, the rate of heart and pancreas procurement increased with a longer delay after the diagnosis of brain death was made. The exact reasons for this finding are unclear. The authors suggested that many more patients were hemodynamically stable for organ procurement with a longer time delay.
These findings are supported by previous studies. It was shown that the graft viability might improve after kidney donation with a longer time allowed to pass after the brain death. Better hemodynamic status and attenuated inflammatory response with longer waiting times were attributed to a better kidney graft function in the recipient.
Of course, better organ procurement rates do not guarantee better organ graft survival in the recipient over time. The findings of this study are encouraging, nevertheless. So far there is no established maximum time between the diagnosis of brain death and organ donation. After all, sooner or later is better than never at all.




